Description
Description: GUSB Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 635 amino acids (23-651a.a) and having a molecular mass of 73.4kDa (Molecular size on SDS-PAGE will appear at approximately 70-100kDa). GUSB is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Introduction: GlucuronidaseBeta (GUSB) is a lysosomal hydrolase which is taking part in the stepwisedegradation of glucuronic acid-containing glycosaminoglycans and plays a significantrole in the degradation of dermatan and keratin sulfates. GUSB is comprised ofheparin sulfate, chondroitin sulfate and hyaluronan